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1

Cycloartane triterpenoids from Cimicifuga yunnanensis induce apoptosis of breast cancer cells (MCF7) via p53-dependent mitochondrial signaling pathway

Zhong-Ze Fang, Yin Nian, Wei Li, Jing-Jing Wu, Guang-Bo Ge, Pei-Pei Dong, Yan-Yan Zhang, Ming-Hua Qiu, Lei Liu, Ling Yang

Journal:

Phytotherapy Research

Year:

2011

Language:

english

File:

PDF, 983 KB

english, 2011

2

Inhibition of human cytochrome P450 enzymes by licochalcone A, a naturally occurring constituent of licorice

He, Wei, Wu, Jing-Jing, Ning, Jing, Hou, Jie, Xin, Hong, He, Yu-Qi, Ge, Guang-Bo, Xu, Wei

Journal:

Toxicology in Vitro

Year:

2015

Language:

english

File:

PDF, 1.53 MB

english, 2015

3

A highly selective ratiometric two-photon fluorescent probe for human cytochrome P450 1A

Dai, Zi-Ru, Ge, Guang-Bo, Feng, Lei, Ning, Jing, Hu, Liang-Hai, Wang, Jia-yue, Jin, Qiang, Wang, Dan-Dan, Lv, Xia, Dou, Tong-Yi, Cui, Jing-Nan, Yang, Ling

Journal:

Journal of the American Chemical Society

Year:

2015

Language:

english

File:

PDF, 904 KB

english, 2015

4

A practical strategy to design and develop an isoform-specific fluorescent probe for a target enzyme: CYP1A1 as a case study

Dai, Zi-Ru, Feng, Lei, Jin, Qiang, Cheng, Hailing, Li, Yan, Ning, Jing, Yu, Yang, Ge, Guang-Bo, Cui, Jing-Nan, Yang, Ling

Journal:

Chemical Science

Year:

2017

Language:

english

File:

PDF, 1.91 MB

english, 2017

5

Anticancer Drug Targets of Salvia Phytometabolites: Chemistry, Biology and Omics

Hao, Da-Cheng, Ge, Guang-Bo, Xiao, Pei-Gen

Journal:

Current Drug Targets

Year:

2018

Language:

english

File:

PDF, 2.22 MB

english, 2018

6

Inhibition of UGT1A1 by natural and synthetic flavonoids

Liu, Xin-Yu, Lv, Xia, Wang, Ping, Ai, Chun-Zhi, Zhou, Qi-Hang, Finel, Moshe, Fan, Bin, Cao, Yun-Feng, Tang, Hui, Ge, Guang-Bo

Journal:

International Journal of Biological Macromolecules

Year:

2019

Language:

english

File:

PDF, 3.76 MB

english, 2019

7

Biflavones from Ginkgo biloba as inhibitors of human thrombin

Chen, Tian-Ran, Wei, Ling-Hua, Guan, Xiao-Qing, Huang, Chao, Liu, Zhe-Yi, Wang, Fang-Jun, Hou, Jie, Jin, Qiang, Liu, Yi-Fan, Wen, Pei-Hao, Zhang, Shui-Jun, Ge, Guang-Bo, Guo, Wen-Zhi

Journal:

Bioorganic Chemistry

Year:

2019

Language:

english

File:

PDF, 3.09 MB

english, 2019

8

Inhibition of pancreatic lipase by the constituents in St. John's Wort: In vitro and in silico investigations

Hou, Xu-Dong, Guan, Xiao-Qing, Cao, Yun-Feng, Weng, Zi-Miao, Hu, Qing, Liu, Hai-Bin, Jia, Shou-Ning, Zang, Shi-Zhu, Zhou, Qi, Yang, Ling, Ge, Guang-Bo, Hou, Jie

Journal:

International Journal of Biological Macromolecules

Year:

2019

Language:

english

File:

PDF, 10.76 MB

english, 2019

9

Discovery and characterization of pentacyclic triterpenoid acids in Styrax as potent and reversible pancreatic lipase inhibitors

Wang, Lu, Guan, Xiao-Qing, He, Rong-jing, Huo, Peng-Chao, Qin, Wei-Wei, Cui, Long-Tao, Hu, Qing, Hou, Jie, Mamat, Mihreay, Jia, Shou-Ning, Tang, Hui, Ge, Guang-Bo

Journal:

Journal of Functional Foods

Year:

2020

File:

PDF, 2.31 MB

2020

10

Quantitative structure-retention relationship studies for taxanes including epimers and isomeric metabolites in ultra fast liquid chromatography

Pei-Pei Dong, Guang-Bo Ge, Yan-Yan Zhang, Chun-Zhi Ai, Guo-Hui Li, Liang-Liang Zhu, Hong-Wei Luan, Xing-Bao Liu, Ling Yang

Journal:

Journal of Chromatography A

Year:

2009

Language:

english

File:

PDF, 321 KB

english, 2009

11

Determination of propofol UDP-glucuronosyltransferase (UGT) activities in hepatic microsomes from different species by UFLC–ESI-MS

Si-Cheng Liang, Guang-Bo Ge, Hui-Xin Liu, Hai-Tao Shang, Hong Wei, Zhong-Ze Fang, Liang-Liang Zhu, Yu-Xi Mao, Ling Yang

Journal:

Journal of Pharmaceutical and Biomedical Analysis

Year:

2011

Language:

english

File:

PDF, 486 KB

english, 2011

12

Identification of cytochrome P450 (CYP) isoforms involved in the metabolism of corynoline, and assessment of its herb–drug interactions

Zhong-Ze Fang, Yan-Yan Zhang, Guang-Bo Ge, Si-Cheng Liang, Dong-Xue Sun, Liang-Liang Zhu, Pei-Pei Dong, Yun-Feng Cao, Ling Yang

Journal:

Phytotherapy Research

Year:

2011

Language:

english

File:

PDF, 402 KB

english, 2011

13

Investigation of UDP-glucuronosyltransferases (UGTs) Inhibitory Properties of Carvacrol

Rui-Hua Dong, Zhong-Ze Fang, Liang-Liang Zhu, Si-Cheng Liang, Guang-Bo Ge, Ling Yang, Ze-Yuan Liu

Journal:

Phytotherapy Research

Year:

2012

Language:

english

File:

PDF, 128 KB

english, 2012

14

Profiling of yew hair roots from various species using ultra-performance liquid chromatography/electrospray ionization mass spectrometry

Guang-Bo Ge, Hong-Wei Luan, Yan-Yan Zhang, Yu-Qi He, Xing-Bao Liu, Li Yang, Zheng-Tao Wang, Ling Yang

Journal:

Rapid Communications in Mass Spectrometry

Year:

2008

Language:

english

File:

PDF, 269 KB

english, 2008

15

Erratum: Profiling of yew hair roots from various species using ultra-performance liquid chromatography/electrospray ionization mass spectrometry

Guang-Bo Ge, Hong-Wei Luan, Yan-Yan Zhang, Yu-Qi He, Xing-Bao Liu, Li Yang, Zheng-Tao Wang, Ling Yang

Journal:

Rapid Communications in Mass Spectrometry

Year:

2008

Language:

english

File:

PDF, 59 KB

english, 2008

16

Stereochemical differentiation of C-7 hydroxyltaxane isomers by electrospray ionization mass spectrometry

Guang-Bo Ge, Rong Zhang, Chun-Zhi Ai, Yu-Qi He, Yan-Yan Zhang, Xing-Bao Liu, Li Yang, Zheng-Tao Wang, Ling Yang

Journal:

Rapid Communications in Mass Spectrometry

Year:

2009

Language:

english

File:

PDF, 353 KB

english, 2009

17

Time-dependent inhibition (TDI) of CYP3A4 and CYP2C9 by noscapine potentially explains clinical noscapine–warfarin interaction

Zhong-Ze Fang, Yan-Yan Zhang, Guang-Bo Ge, Hong Huo, Si-Cheng Liang, Ling Yang

Journal:

British Journal of Clinical Pharmacology

Year:

2010

Language:

english

File:

PDF, 580 KB

english, 2010

18

Modeling resistance index of taxoids to MCF-7 cell lines using ANN together with electrotopological state descriptors

Pei-pei DONG, Yan-yan ZHANG, Guang-bo GE, Chun-zhi AI, Yong LIU, Ling YANG, Chang-xiao LIU

Journal:

Acta Pharmacologica Sinica

Year:

2008

Language:

english

File:

PDF, 419 KB

english, 2008

19

The Inhibitory Effect of 20(S)-Protopanaxatriol (ppt) Towards UGT1A1 and UGT2B7

Ya-Jun He, Zhong-Ze Fang, Guang-Bo Ge, Peng Jiang, Hui-Zi Jin, Wei-Dong Zhang, Ling Yang

Journal:

Phytotherapy Research

Year:

2012

Language:

english

File:

PDF, 179 KB

english, 2012

20

Rapid profiling and target analysis of principal components in Fuling Decoctions by UFLC-DAD-ESI-MS

Ao-Xue Wang, Guang-Bo Ge, Xiao-Yi Qi, Ying Hu, Si-Cheng Liang, Ling Yang, Cai-Xia Tu

Journal:

Year:

2010

Language:

english

File:

PDF, 365 KB

english, 2010

21

Isolation and characterization of a novel α-glucosidase with transglycosylation activity from Arthrobacter sp. DL001

Kun Zhou, Hong-wei Luan, Ying Hu, Guang-bo Ge, Xing-bao Liu, Xiao-chi Ma, Jie Hou, Xiu-li Wang, Ling Yang

Journal:

Journal of Molecular Catalysis B: Enzymatic

Year:

2012

Language:

english

File:

PDF, 850 KB

english, 2012

22

Biological, Chemical, and Omics Research of Taxus Medicinal Resources

Hao, Da-Cheng, Xiao, Pei-Gen, Ge, Guang-Bo, Liu, Ming

Journal:

Drug Development Research

Year:

2012

Language:

english

File:

PDF, 144 KB

english, 2012

23

Inhibitory effects of sanguinarine on human liver cytochrome P450 enzymes

Qi, Xiao-Yi, Liang, Si-Cheng, Ge, Guang-Bo, Liu, Yong, Dong, Pei-Pei, Zhang, Jiang-Wei, Wang, Ao-Xue, Hou, Jie, Zhu, Liang-Liang, Yang, Ling, Tu, Cai-Xia

Journal:

Food and Chemical Toxicology

Year:

2013

Language:

english

File:

PDF, 997 KB

english, 2013

24

The Negative Co-Signaling Molecule B7-H4 Is Expressed by Human Bone Marrow–Derived Mesenchymal Stem Cells and Mediates its T-Cell Modulatory Activity

Xue, Qun, Luan, Xi-Ying, Gu, Yan-Zheng, Wu, Hong-Ya, Zhang, Guang-Bo, Yu, Ge-Hua, Zhu, Hua-Ting, Wang, Mingyuan, Dong, Wanli, Geng, Yong-Jian, Zhang, Xue-Guang

Journal:

Stem Cells and Development

Year:

2010

Language:

english

File:

PDF, 952 KB

english, 2010

25

A continued saga of Boc5, the first non-peptidic glucagon-like peptide-1 receptor agonist with in vivo activities

He, Min, Guan, Ni, Gao, Wei-wei, Liu, Qing, Wu, Xiao-yan, Ma, Da-wei, Zhong, Da-fang, Ge, Guang-bo, Li, Chuan, Chen, Xiao-yan, Yang, Ling, Liao, Jia-yu, Wang, Ming-wei

Journal:

Acta Pharmacologica Sinica

Year:

2012

Language:

english

File:

PDF, 2.51 MB

english, 2012

26

A highly selective probe for human cytochrome P450 3A4: isoform selectivity, kinetic characterization and its applications

Ge, Guang-Bo, Ning, Jing, Hu, Liang-Hai, Dai, Zi-Ru, Hou, Jie, Cao, Yun-Feng, Yu, Zhen-Wen, Ai, Chun-Zhi, Gu, Jing-Kai, Ma, Xiao-Chi, Yang, Ling

Journal:

Chemical Communications

Year:

2013

Language:

english

File:

PDF, 1.34 MB

english, 2013

27

The role of serum albumin in the metabolism of Boc5: Molecular identification, species differences and contribution to plasma metabolism

Ge, Guang-Bo, Ai, Chun-Zhi, Hu, Wen-Bing, Hou, Jie, Zhu, Liang-Liang, He, Gui-Yuan, Fang, Zhong-Ze, Liang, Si-Cheng, Wang, Fu-Yi, Yang, Ling

Journal:

European Journal of Pharmaceutical Sciences

Year:

2013

Language:

english

File:

PDF, 940 KB

english, 2013

28

A highly selective ratiometric fluorescent probe for in vitro monitoring and cellular imaging of human carboxylesterase 1

Liu, Zhao-Ming, Feng, Lei, Ge, Guang-Bo, Lv, Xia, Hou, Jie, Cao, Yun-Feng, Cui, Jing-Nan, Yang, Ling

Journal:

Biosensors and Bioelectronics

Year:

2014

Language:

english

File:

PDF, 1.29 MB

english, 2014

29

New insights for the risk of bisphenol A: Inhibition of UDP-glucuronosyltransferases (UGTs)

Jiang, Hua-Mao, Fang, Zhong-Ze, Cao, Yun-Feng, Hu, Cui-Min, Sun, Xiao-Yu, Hong, Mo, Yang, Ling, Ge, Guang-Bo, Liu, Yong, Zhang, Yan-Yan, Dong, Qiang, Liu, Ren-Jie

Journal:

Year:

2013

Language:

english

File:

PDF, 1.16 MB

english, 2013

30

Structure–inhibition relationship of ginsenosides towards UDP-glucuronosyltransferases (UGTs)

Fang, Zhong-Ze, Cao, Yun-Feng, Hu, Cui-Min, Hong, Mo, Sun, Xiao-Yu, Ge, Guang-Bo, Liu, Yong, Zhang, Yan-Yan, Yang, Ling, Sun, Hong-Zhi

Journal:

Toxicology and Applied Pharmacology

Year:

2013

Language:

english

File:

PDF, 832 KB

english, 2013

31

A highly selective fluorescent ESIPT probe for the detection of Human carboxylesterase 2 and its biological applications

Feng, Lei, Liu, Zhao-Ming, Hou, Jie, Lv, Xia, Ning, Jing, Ge, Guang-Bo, Cui, Jing-Nan, Yang, Ling

Journal:

Biosensors and Bioelectronics

Year:

2015

Language:

english

File:

PDF, 2.20 MB

english, 2015

32

A ratiometric fluorescent sensor for highly selective detection of human carboxylesterase 2 and its application in living cells

Liu, Zhao-Ming, Feng, Lei, Hou, Jie, Lv, Xia, Ning, Jing, Ge, Guang-Bo, Wang, Ke-Wei, Cui, Jing-Nan, Yang, Ling

Journal:

Sensors and Actuators B: Chemical

Year:

2014

Language:

english

File:

PDF, 1011 KB

english, 2014

33

Deep understanding of the interaction between thienorphine and UDP-glucuronosyltransferase (UGT) isoforms

Dong, Rui-Hua, Fang, Zhong-Ze, Zhu, Liang-Liang, Ge, Guang-Bo, Li, Xiao-Bao, Hu, Cui-Min, Cao, Yun-Feng, Xia, Yang-Liu, Yang, Ling, Liu, Ze-Yuan

Journal:

Year:

2013

Language:

english

File:

PDF, 857 KB

english, 2013

34

Glucuronidation of the broad-spectrum antiviral drug arbidol by UGT isoforms

Song, Jin-Hui, Fang, Zhong-Ze, Zhu, Liang-Liang, Cao, Yun-Feng, Hu, Cui-Min, Ge, Guang-Bo, Zhao, De-Wei

Journal:

Journal of Pharmacy and Pharmacology

Year:

2013

Language:

english

File:

PDF, 589 KB

english, 2013

35

A highly selective long-wavelength fluorescent probe for the detection of human carboxylesterase 2 and its biomedical applications

Feng, Lei, Liu, Zhao-Ming, Xu, Liang, Lv, Xia, Ning, Jing, Hou, Jie, Ge, Guang-Bo, Cui, Jing-Nan, Yang, Ling

Journal:

Chemical Communications

Year:

2014

Language:

english

File:

PDF, 1.80 MB

english, 2014

36

Fructus Psoraleae contains natural compounds with potent inhibitory effects towards human carboxylesterase 2

Li, Yao-Guang, Hou, Jie, Li, Shi-Yang, Lv, Xia, Ning, Jing, Wang, Ping, Liu, Zhao-Ming, Ge, Guang-Bo, Ren, Jia-Yan, Yang, Ling

Journal:

Year:

2015

Language:

english

File:

PDF, 952 KB

english, 2015

37

Substrate-dependent modulation of the catalytic activity of CYP3A by erlotinib

Dong, Pei-pei, Fang, Zhong-ze, Zhang, Yan-yan, Ge, Guang-bo, Mao, Yu-xi, Zhu, Liang-liang, Qu, Yan-qing, Li, Wei, Wang, Li-ming, Liu, Chang-xiao, Yang, Ling

Journal:

Acta Pharmacologica Sinica

Year:

2011

Language:

english

File:

PDF, 1.05 MB

english, 2011

38

A highly selective probe for UDP-glucuronosyltransferase 2B7 (UGT2B7) in human microsomes: isoform specificity, kinetic characterization, and applications

Tian, Xiang-Ge, Wang, Chao, Ge, Guang-Bo, Ning, Jing, Ai, Chun-Zhi, Hong, James Y., Cai, Yong-Xv, Huo, Xiao-Kui, Hou, Jie, Liu, Ke-Xin, Sun, Hong-Zhi, Ma, Xiao-Chi

Journal:

Year:

2015

Language:

english

File:

PDF, 392 KB

english, 2015

39

An optimized ratiometric fluorescent probe for sensing human UDP-glucuronosyltransferase 1A1 and its biological applications

Lv, Xia, Ge, Guang-Bo, Feng, Lei, Troberg, Johanna, Hu, Liang-Hai, Hou, Jie, Cheng, Hai-Ling, Wang, Ping, Liu, Zhao-Ming, Finel, Moshe, Cui, Jing-Nan, Yang, Ling

Journal:

Biosensors and Bioelectronics

Year:

2015

Language:

english

File:

PDF, 935 KB

english, 2015

40

Identification of UDP-glucuronosyltransferase isoforms involved in hepatic and intestinal glucuronidation of phytochemical carvacrol

Dong, Rui-Hua, Fang, Zhong-Ze, Zhu, Liang-Liang, Ge, Guang-Bo, Yang, Ling, Liu, Ze-Yuan

Journal:

Year:

2012

Language:

english

File:

PDF, 914 KB

english, 2012

41

Glucuronidation of aurantio-obtusin: identification of human UDP-glucuronosyltransferases and species differences

Mi, Bao-Li, Sun, Qi, Qu, Yan-Qing, Gao, Xiao-Xu, Yu, Zhen-Wen, Ge, Guang-Bo, Cai, Shan-Shan, Zhang, Jie, Zheng, Yan-Chao, Zhang, Zhen-Qiu

Journal:

Year:

2014

Language:

english

File:

PDF, 359 KB

english, 2014

42

Design, synthesis and biological evaluation of esculetin derivatives as anti-tumour agents

Wang, Ping, Xia, Yang-Liu, Yu, Yang, Lu, Jun-Xia, Zou, Li-Wei, Feng, Lei, Ge, Guang-Bo, Yang, Ling

Journal:

Year:

2015

Language:

english

File:

PDF, 857 KB

english, 2015

43

Identifying and applying a highly selective probe to simultaneously determine the O-glucuronidation activity of human UGT1A3 and UGT1A4

Jiang, Li, Liang, Si-Cheng, Wang, Chao, Ge, Guang-Bo, Huo, Xiao-Kui, Qi, Xiao-Yi, Deng, Sa, Liu, Ke-Xin, Ma, Xiao-Chi

Journal:

Scientific Reports

Year:

2015

Language:

english

File:

PDF, 581 KB

english, 2015

44

Interspecies variation in phase I metabolism of bufalin in hepatic microsomes from mouse, rat, dog, minipig, monkey, and human

Ning, Jing, Hou, Jie, Wang, Ping, Wu, Jing-Jing, Dai, Zi-Ru, Zou, Li-Wei, Li, Wei, Ge, Guang-Bo, Ma, Xiao-Chi, Yang, Ling

Journal:

Year:

2015

Language:

english

File:

PDF, 340 KB

english, 2015

45

Rapid Qualitative and Quantitative Determination of Seven Valuable Taxanes from Various Taxus Species by UFLC‐ESI‐MS and UFLC‐DAD

Ge, Guang-Bo, Liang, Si-Cheng, Hu, Ying, Liu, Xing-Bao, Mao, Yu-Xi, Zhang, Yan-Yan, Luan, Hong-Wei, Qiu, Ming-Hua, Yang, Ling

Journal:

Year:

2010

Language:

english

File:

PDF, 120 KB

english, 2010

46

Glucuronidation of bavachinin by human tissues and expressed UGT enzymes: Identification of UGT1A1 and UGT1A8 as the major contributing enzymes

Lv, Xia, Hou, Jie, Xia, Yang-Liu, Ning, Jing, He, Gui-Yuan, Wang, Ping, Ge, Guang-Bo, Xiu, Zhi-Long, Yang, Ling

Journal:

Drug Metabolism and Pharmacokinetics

Year:

2015

Language:

english

File:

PDF, 1.12 MB

english, 2015

47

Gomisin A is a Novel Isoform-Specific Probe for the Selective Sensing of Human Cytochrome P450 3A4 in Liver Microsomes and Living Cells

Wu, Jing-Jing, Ge, Guang-Bo, He, Yu-Qi, Wang, Ping, Dai, Zi-Ru, Ning, Jing, Hu, Liang-Hai, Yang, Ling

Journal:

The AAPS Journal

Year:

2016

Language:

english

File:

PDF, 1.15 MB

english, 2016

48

Protostane Triterpenoids from the Rhizome of Alisma orientale Exhibit Inhibitory Effects on Human Carboxylesterase 2

Mai, Zhen-Peng, Zhou, Kun, Ge, Guang-Bo, Wang, Chao, Huo, Xiao-Kui, Dong, Pei-Pei, Deng, Sa, Zhang, Bao-Jing, Zhang, Hou-Li, Huang, Shan-Shan, Ma, Xiao-Chi

Journal:

Journal of Natural Products

Year:

2015

Language:

english

File:

PDF, 2.21 MB

english, 2015

49

Chemotaxonomic Study of Medicinal Taxus Species with Fingerprint and Multivariate Analysis

Ge, Guang-Bo, Zhang, Yan-Yan, Hao, Da-Cheng, Hu, Ying, Luan, Hong-Wei, Liu, Xing-Bao, He, Yu-Qi, Wang, Zheng-Tao, Yang, Ling

Journal:

Year:

2008

Language:

english

File:

PDF, 532 KB

english, 2008

50

Inhibition behavior of fructus psoraleae’s ingredients towards human carboxylesterase 1 (hCES1)

Sun, Dong-Xue, Ge, Guang-Bo, Dong, Pei-Pei, Cao, Yun-Feng, Fu, Zhi-Wei, Ran, Rui-Xue, Wu, Xue, Zhang, Yan-Yan, Hua, Hui-Ming, Zhao, Zhenying, Fang, Zhong-Ze

Journal:

Year:

2015

Language:

english

File:

PDF, 1005 KB

english, 2015

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